NO Synthase
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NO Synthase Inhibitors
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NO Synthase Agonists
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NO Synthase Antagonists
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NO Synthase Activators
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NO Synthase Modulators
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NO Synthase MDM2 Inhibitor
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NO Synthase Controls
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NO Synthase Substrates
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NO Synthase Ligand
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NO Synthase Related Products (626)
Related Products (626)
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L-NMMA acetate (Standard)
0 ImagesSynonyms: Tilarginine acetate (Standard); Methylarginine acetate (Standard)L-NMMA (Tilarginine) acetate (Standard) is the analytical standard of L-NMMA acetate (HY-18732A). This product is intended for research and analytical applications. L-NMMA (Tilarginine) acetate is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA acetate inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production. L-NMMA acetate alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA acetate is applicable to research related to nociception, bone cancer pain, and myopia.
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Phenyl β-D-glucopyranoside (Standard)
0 ImagesPhenyl β-D-glucopyranoside (Standard) is the analytical standard of Phenyl β-D-glucopyranoside (HY-W011849). This product is intended for research and analytical applications. Phenyl β-D-glucopyranoside is a component isolated from Phellodendron amurense, which has anti-inflammatory and anti-tumor activities. Phenyl β-D-glucopyranoside inhibits nitric oxide (NO) production, and the expression of iNOS and COX-2. Phenyl β-D-glucopyranoside also inhibits the nuclear translocation of NF-κB. Phenyl β-D-glucopyranoside inhibits the expression of pro-inflammatory cytokines and related genes.
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Methyl 5-hydroxypyridine-2-carboxylate (Standard)
0 ImagesCat. No.: HY-W005963RCAS No.: 30766-12-2Methyl 5-hydroxypyridine-2-carboxylate (Standard) is the analytical standard of Methyl 5-hydroxypyridine-2-carboxylate (HY-W005963). This product is intended for research and analytical applications. Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro.
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Lubiprostone-d7
0 ImagesCat. No.: HY-B0679SCAS No.: 1217675-13-2Synonyms: RU-0211-d7; SPI-0211-d7Lubiprostone-d7 (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research.
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NO-Rosa5 chloride
0 ImagesCat. No.: HY-172755Synonyms: Nitric Oxide-Rosa5 chlorideNO-Rosa5 (chloride) is a photocontrollable NO donor. NO-Rosa5 (chloride) is made up of the fluorescent dye rosamie that functions as the light-harvesting group.
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ARL 17477 (Standard)
0 ImagesCat. No.: HY-107720RCAS No.: 866914-87-6ARL 17477 (Standard) is the analytical standard of ARL 17477 (HY-107720). This product is intended for research and analytical applications. ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers.
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Saquinavir-13C6
0 ImagesCat. No.: HY-17007S2Synonyms: Ro 31-8959-13C6Saquinavir-13C6 (Ro 31-8959-13C6) is 13C labeled Saquinavir (HY-17007). Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells.
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Anti-inflammatory agent 63
0 ImagesCat. No.: HY-149671CAS No.: 2347694-79-3Anti-inflammatory agent 63 is an anti-inflammatory agent that shows optimal inhibitory activity (EC50 = 5.33±0.57 μM) against the production of nitric oxide (NO) induced by lipopolysaccharide (LPS) in RAW264.7 cells.
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Nalmefene (Standard)
0 ImagesCat. No.: HY-107744RCAS No.: 55096-26-9Nalmefene (Standard) is the analytical standard of Nalmefene. This product is intended for research and analytical applications. Nalmefene is a long acting opioid (MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence.
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Tricrozarin A
0 ImagesCat. No.: HY-N15334CAS No.: 107817-60-7Tricrozarin A is a Naphthazarin (HY-N7526) derivative, which is found in fresh bulbs of Tritonia crocosmaeflora. Tricrozarin A exhibits antimicrobial activity against gram-positive bacteria, fungi, and yeast.
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DHEA Benzophenone-biotin
0 ImagesCat. No.: HY-183342CAS No.: 1216903-70-6DHEA Benzophenone-biotin is a photoactive DHEA (HY-14650) analog containing Biotin (HY-B0511) and Benzophenone (HY-Y0546) groups. DHEA Benzophenone-biotin inhibits plasma membrane binding of DHEA, activates endothelial NO synthase. DHEA Benzophenone-biotin cross-links to plasma membrane DHEA binding sites upon UV irradiation to identify associated proteins.
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Piceatannol 3'-O-glucoside (Standard)
0 ImagesCat. No.: HY-N2237RCAS No.: 94356-26-0Synonyms: Quzhaqigan (Standard)Piceatannol 3'-O-glucoside (Standard) is the analytical standard of Piceatannol 3'-O-glucoside. This product is intended for research and analytical applications. Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelial nitric oxide (NO) synthase through inhibition of arginase activity with IC50s of 11.22 μM and 11.06 μM against arginase I and arginase II, respectively.
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Aminoguanidine-13C,15N4 hemisulfate
0 ImagesCat. No.: HY-W020772AS1Purity: 99.0%Synonyms: Pimagedine-13C,15N4 hemisulfate; GER-11-13C,15N4 hemisulfate; Aminoguanidinium-13C,15N4 hemisulfateAminoguanidine-13C,15N4 (Pimagedine-13C,15N4) hemisulfate is the 13C,15N4-labeled Aminoguanidine hemisulfate (HY-W020772). Aminoguanidine hemisulfate is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hemisulfate can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hemisulfate has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hemisulfate has antioxidant properties. Aminoguanidine hemisulfate can be used in the research of diabetic nephropathy.
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Rubranol
0 ImagesCat. No.: HY-N1330CAS No.: 211126-61-3Rubranol is an inhibitor of NO Synthase. Rubranol inhibits LPS-induced NO production in activated macrophages with 74% inhibition.
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trans-Isoferulic acid (Standard)
0 ImagesSynonyms: trans-3-Hydroxy-4-methoxycinnamic acid (Standard)trans-Isoferulic acid (Standard) is the analytical standard of trans-Isoferulic acid. This product is intended for research and analytical applications. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity.trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1).
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α-Humulene (Standard)
0 ImagesSynonyms: Humulene (Standard); α-Caryophyllene (Standard)α-Humulene (Standard) is the analytical standard of α-Humulene. This product is intended for research and analytical applications. α-Humulene is a main constituent of Tanacetum vulgare L. (Asteraceae) essential oil with anti-inflammation (IC50=15±2 μg/mL). α-Humulene inhibits COX-2 and iNOS expression.
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Quinocetone (Standard)
0 ImagesCat. No.: HY-123581RCAS No.: 81810-66-4Quinocetone (Standard) is the analytical standard of Quinocetone (HY-123581). This product is used for research and analytical purposes. Quinocetone is an orally active animal feed additive used to increase the meat production of livestock and poultry. Quinocetone exhibits antibacterial activity against a variety of pathogenic microorganisms. Quinocetone exhibits tissue-specific (liver, lymphocyte) toxicity. Quinocetone induces autophagy in cells through the ATF6/DAPK1 pathway. Quinocetone activates the NF-κB and iNOS pathways, leading to cell apoptosis, hepatocyte vacuolar degeneration and fibrosis. Quinocetone can inhibit Nrf2/HO-1 and induce the generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage.
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3β,15α-Dihydroxy-7,11,23-trioxo-lanost-8-dien-26-oic acid
0 ImagesCat. No.: HY-N13706CAS No.: 117354-72-03β,15α-Dihydroxy-7,11,23-trioxo-lanost-8-dien-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 6.50 μM, making it a potential candidate for anti-inflammatory research.
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Artocarpesin
0 ImagesArtocarpesin is a flavonoid compound. Artocarpesin has inhibitory effects on methicillin-resistant Staphylococcus aureus (MRSA). Artocarpesin inhibits the production of NO, PGE2 and ROS by inhibiting COX-2 and iNOS expression, and plays an anti-inflammatory role. In addition, Artocarpesin inhibits platelet aggregation by inhibiting cyclic nucleotides and MAPKs, which can be used in the study of cardiovascular diseases.
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GYY4137 (Standard)
0 ImagesCat. No.: HY-107632RCAS No.: 106740-09-4GYY4137 (Standard) is the analytical standard of GYY4137 (HY-107632). This product is intended for research and analytical applications. GY4137 is a sustained-release H2S donor possessing vasodilatory, antihypertensive, and anti-inflammatory activities. GY4137 can inhibit cell growth, induce apoptosis, and cause cell cycle arrest by blocKing the STAT3 pathway, demonstrating potent anticancer activity.
